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Why Histidine is triprotic under biological condition?

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what would be the correct choice?

Under most biological conditions, however, histidine is considered to be a triprotic acid. This is due to the pKa of the _________ .

A. Other nitrogen in the imidazole ring, that possesses a hydrogen but no charge being much lower than the pH values normally found in a cell.

B. Other nitrogen in the imidazole ring, that possesses a hydrogen but no charge being much higher than the pH values normally found in a cell.

C. Carboxylic acid being much...

Why Histidine is triprotic under biological condition?

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