Question about insulin resistance

I understand why I got this question wrong: the antibiotic treatment would eliminate gut biota and have the same effect of knocking out the GPCR talked about in the passage, leading to weight gain, and thus an increase in adipocyte size.

I want to make sure I understand insulin sensitivity/resistance. So being insulin resistant is unhealthy (diabetes) because your body produces excess insulin to try and pick up glucose, but glucose uptake does not occur at a high enough rate.

So for this...

Question about insulin resistance