Water bound to which of the four hemes was most likely shown to have the lowest pKa?
A. Native H-NOX correct answer
B. Mutant 1
C. Mutant 2
D. Mutant 3
The explanation is: "Since all of the iron atoms are in the same formal oxidation state (+3), the changes in redox potential speak to the relative electron deficiency of each iron. A large positive redox potential indicates an easily reducible, electron deficient, iron center. The rules regarding inductive effects apply in...
TPR Inductive effect + pKa
A. Native H-NOX correct answer
B. Mutant 1
C. Mutant 2
D. Mutant 3
The explanation is: "Since all of the iron atoms are in the same formal oxidation state (+3), the changes in redox potential speak to the relative electron deficiency of each iron. A large positive redox potential indicates an easily reducible, electron deficient, iron center. The rules regarding inductive effects apply in...
TPR Inductive effect + pKa